| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1153 | |
| Phytochemical name or plant extracts | Parkinsonia aculeata extract | |
| PMID | 32922145 | |
| Literature evidence | Accordingly, the most active fraction was the ethyl acetate which showed the highest antioxidant activity (SC50 = 57.4 ± 1.2 μg/mL) compared with the positive control, ascorbic acid (SC50 = 12.4 ± 0.5 μg/mL) and moderate cytotoxicity against HepG-2 (hepatocellular carcinoma) and MCF-7 (breast carcinoma) cell lines with IC50 = 56.9 ± 3.1 and 95.8 ± 3.8 μg/mL, respectively compared with cisplatin (IC50 = 3.67 ± 0.22 and 5.71 ± 0.57 μg/mL, respectively for both cell lines). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hydroalcoholic extract, dichloromethane, and ethyl acetate fractions | |
| Source of phytochemicals or plant Extracts | Parkinsonia aculeata | |
| Geographical availability | Argentina Northeast, Argentina Northwest, Arizona, Aruba, Bahamas, Belize, Bolivia, Brazil South, California, Colombia, Cuba, Dominican Republic, Ecuador, El Salvador, Florida, Galápagos, Georgia, Guatemala, Haiti, Honduras, Jamaica, Leeward Is., Louisiana, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mississippi, Netherlands Antilles, Nevada, Paraguay, Peru, Puerto Rico, South Carolina, Southwest Caribbean, Texas, Turks-Caicos Is., Uruguay, Utah, Venezuelan Antilles, Windward Is. | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 95.8 ± 3.8 μg/mL against MCF-7 | |
| Potency | Accordingly, the most active fraction was the ethyl acetate which showed the highest antioxidant activity (SC50 = 57.4 ± 1.2 μg/mL) compared with the positive control, ascorbic acid (SC50 = 12.4 ± 0.5 μg/mL) and moderate cytotoxicity against HepG-2 (hepatocellular carcinoma) and MCF-7 (breast carcinoma) cell lines with IC50 = 56.9 ± 3.1 and 95.8 ± 3.8 μg/mL, respectively compared with cisplatin (IC50 = 3.67 ± 0.22 and 5.71 ± 0.57 μg/mL, respectively for both cell lines). | |
| Cell line/ mice model | MCF-7, HepG-2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:512242-1 | |
| Safety | NA |