Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1361 | |
Phytochemical name or plant extracts | Papaya leaf extract | |
PMID | 29023013 | |
Literature evidence | Papaya leaf extract can also induce apoptosis of breast cancer cells MCF-7 about 22.54% for concentration 659.63 ?g mL-1 and about 20.73% for concentration 329.81 ?g mL-1. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Aqueous Extract | |
Source of phytochemicals or plant Extracts | Carica papaya | |
Geographical availability | Belize, Colombia, Costa Rica, El Salvador, Guatemala, Honduras, Mexico Gulf, Mexico Southeast, Mexico Southwest, Nicaragua, Panamá, Venezuela | |
Plant parts | Leaves | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 1319.25 µg/mL against MCF-7 | |
Potency | This study indicated that papaya leaf extract have potential as anticancer through mechanism anti-proliferation and apoptosis induction. | |
Cell line/ mice model | MCF-7 | |
Additional information | Papaya leaf extract can also induce apoptosis of breast cancer cells MCF-7 about 22.54% for concentration 659.63 µg mL-1 and about 20.73% for concentration 329.81 µg mL-1. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30011248-2 | |
Safety | NA |