| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-949 | |
| Phytochemical name or plant extracts | Oplopandiol | |
| PMID | 23746754 | |
| Literature evidence | Results from this study supplied valuable information for future semi-synthesis of polyyne derivatives to develop novel cancer chemopreventive agents. | |
| IUPAC name | (Z,3S,8S)-heptadec-9-en-4,6-diyne-3,8-diol | |
| Phytochemicals’ class or type of plant extracts | Polyynes | |
| Source of phytochemicals or plant Extracts | Oplopanax horridus | |
| Geographical availability | Alaska, Alberta, British Columbia, Idaho, Michigan, Montana, Ontario, Oregon, Washington, Yukon | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Colon cancer, colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | These compounds showed potential anticancer activities on human breast cancer and colon cancer cells, of which compound 3 possesses the strongest activity. | |
| Cell line/ mice model | MCF-7 (RPMI-1640), HCT-116 and SW-480 , IEC-6 | |
| Additional information | NA | |
| PubChem ID | 6474833 | |
| Additional PMIDs | 20723598 29766799 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:91131-1 | |
| Safety | NA |