| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1149 | |
| Phytochemical name or plant extracts | Oplopanax horridus extract | |
| PMID | 19686820 | |
| Literature evidence | High performance liquid chromatographic analysis and anticancer potential of Oplopanax horridus: comparison of stem and berry extracts. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Oplopanax horridus | |
| Geographical availability | Alaska, Alberta, British Columbia, Idaho, Michigan, Montana, Ontario, Oregon, Washington, Yukon | |
| Plant parts | Root bark, Stem and Fruits | |
| Other cancers | Breast cancer, Colorectal cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | The IC(50) of the total extract, 50, 70, and 100% ethanol fractions for antiproliferation on MCF-7 cells were 248.4, 123.1, 44.0, and 31.5 microg/mL, respectively, and on NSCLC cells were 125.3, 271.1, 17.6, and 23.2 microg/mL, respectively. | |
| Potency | Interestingly, the root bark extract of O. horridus showed antiproliferative effects on human breast and leukemia cell lines | |
| Cell line/ mice model | SW-480, HCT-116, HT-29, MCF-7, NSCLC | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | 20077432 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:91131-1 | |
| Safety | NA |