| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-905 | |
| Phytochemical name or plant extracts | Oliveria decumbens essential oil | |
| PMID | 31089376 | |
| Literature evidence | O. decumbens essential oil was considerably inhibitory to acetylcholinesterase activity (IC50 = 0.117 µg/mL). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Oliveria decumbens | |
| Geographical availability | Iran, Iraq, Lebanon-Syria, Turkey | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.065 μg/mL against MCF-7 0.104 μg/mL against T47D 0.141 μg/mL against MDA- MB-231 | |
| Potency | Therefore, the cell viability studies demonstrated that OEO/thymol is potent anti-proliferative compound in proliferating breast cancer cells, in a dose-dependent manner | |
| Cell line/ mice model | MCF-7, T47D, MDA- MB-231 | |
| Additional information | We observed significant antibacterial activity of the essential oil against H. pylori (MIC=20.4 µg /mL) as well as other tested bacteria, except for Pseudomonas aeruginosa. O. decumbens essential oil showed significant toxicity to cabbage looper larvae with LD50 value of 52.1 µg /larva following topical and fumigant administration. O. decumbens essential oil was considerably inhibitory to acetylcholinesterase activity (IC50 = 0.117 µg/mL). | |
| PubChem ID | NA | |
| Additional PMIDs | 30361692 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:845406-1 | |
| Safety | NA |