| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1546 | |
| Phytochemical name or plant extracts | Oleamide | |
| PMID | 33333817 | |
| Literature evidence | This study identified 10 candidate compounds that may have potential in the field of anticancer substances. | |
| IUPAC name | (Z)-octadec-9-enamide | |
| Phytochemicals’ class or type of plant extracts | Fatty amide | |
| Source of phytochemicals or plant Extracts | Moringa oleifera | |
| Geographical availability | India, Pakistan | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | Bcl-2 | |
| Gene or Protein evidence | Our findings suggest that oleamide has strongest potential as an anticancer treatment by induce apoptosis through suppress Bcl-2 expression and subsequently promote activation of caspase 3. | |
| Target pathways | Apoptosis pathway | |
| IC50 | NA | |
| Potency | The results suggested that oleamide has potential as an anticancer treatment for MDA-MB-231 TNBC and other cell lines. Oleamide exhibits the strongest anticancer activity when compared to the other two compounds. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | Moreover, oleamide has been reported to inhibit gap junction communication on human breast cancer MDA-MB-231 cells | |
| PubChem ID | 5283387 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:584736-1 | |
| Safety | NA |