| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-945 | |
| Phytochemical name or plant extracts | Ochradenus arabicus extract | |
| PMID | 26981004 | |
| Literature evidence | However, its treatment alone does not induce oxidative stress while doxorubicin increases the level of oxidative stress in MCF-7 cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Ochradenus arabicus | |
| Geographical availability | Gulf States, Iran, Oman, Saudi Arabia, Yemen | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 562 μg/ml against MCF-7 | |
| Potency | Whereas, simultaneous treatment of plant extract and doxorubicin significantly (p < 0.05) decreased the level of intracellular reactive oxygen species (ROS) and lipid peroxidation while an increase in the reduced glutathione and superoxide dismutase activity was observed in time and dose dependent manner. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | The MTT assay data showed that the extract is moderately toxic to the MCF-7 cells. However, its treatment alone does not induce oxidative stress while doxorubicin increases the level of oxidative stress in MCF-7 cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:904757-1 | |
| Safety | NA |