Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1520 | |
Phytochemical name or plant extracts | Nitidulin | |
PMID | 27604296 | |
Literature evidence | Compound 5 showed significant cytotoxicity against all of the tested cancer cell lines, with IC50 values in the range 3.47-9.76 µM. | |
IUPAC name | 3-methoxy-6-[8-methyl-8-(4-methylpent-3-enyl)-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,2-diol | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Dalbergia velutina | |
Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, Laos, Malaya, Myanmar, Thailand, Vietnam | |
Plant parts | Root | |
Other cancers | Breast cancer, Mouth cancer, Cervical cancer, Liver cancer, Colon cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 4.17 ± 0.07 µM against MCF-7 | |
Potency | Shows significant cytotoxicity against KB, HeLa-S3, MCF-7, HepG-2, and HT-29 cell lines | |
Cell line/ mice model | KB, HeLa-S3, MCF-7, HepG-2, and HT-29 | |
Additional information | NA | |
PubChem ID | 630902 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:490515-1 | |
Safety | NA |