Phytochemical Name : Nitidulin

Properties Information
PhytoCAT-ID PhytoCAT-1520
Phytochemical name or plant extracts Nitidulin
PMID 27604296
Literature evidence Compound 5 showed significant cytotoxicity against all of the tested cancer cell lines, with IC50 values in the range 3.47-9.76 µM.
IUPAC name 3-methoxy-6-[8-methyl-8-(4-methylpent-3-enyl)-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,2-diol
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Dalbergia velutina
Geographical availability Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, Laos, Malaya, Myanmar, Thailand, Vietnam
Plant parts Root
Other cancers Breast cancer, Mouth cancer, Cervical cancer, Liver cancer, Colon cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 4.17 ± 0.07 µM against MCF-7
Potency Shows significant cytotoxicity against KB, HeLa-S3, MCF-7, HepG-2, and HT-29 cell lines
Cell line/ mice model KB, HeLa-S3, MCF-7, HepG-2, and HT-29
Additional information  NA
PubChem ID 630902
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:490515-1
Safety NA