| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-154 | |
| Phytochemical name or plant extracts | Nepetin | |
| PMID | 22418930 | |
| Literature evidence | Methylated quercetins isolated from Inula viscosa have improved anticancer and antimicrobial properties compared with other flavonoids and are promising as potential anticancer and antimicrobial agents. | |
| IUPAC name | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Inula britannica | |
| Geographical availability | Albania, Altay, Amur, Austria, Baltic States, Belarus, Belgium, Bulgaria, Buryatiya, Central European Rus, China North-Central, China South-Central, China Southeast, Chita, Corse, Czechoslovakia, Denmark, East European Russia, France, Germany, Great Britain, Greece, Hainan, Hungary, Inner Mongolia, Iran, Iraq, Ireland, Irkutsk, Italy, Japan, Kazakhstan, Khabarovsk, Kirgizstan, Korea, Krasnoyarsk, Krym, Magadan, Manchuria, Mongolia, Nepal, Netherlands, North Caucasus, North European Russi, Northwest European R, Norway, Poland, Portugal, Primorye, Qinghai, Romania, Sakhalin, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Tibet, Transcaucasus, Turkey, Turkey-in-Europe, Turkmenistan, Tuva, Ukraine, Uzbekistan, West Himalaya, West Siberia, Xinjiang, Yakutskiya, Yugoslavia | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Larynx cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 5.87µg/mL against MCF-7 | |
| Potency | The most potent compound was nepetin, with IC50 values of 5.87, 11.33, and 103.54 µg/mL against MCF-7, Hep-2, and Vero cell lines, respectively | |
| Cell line/ mice model | MCF-7, Hep-2, Vero cell | |
| Additional information | NA | |
| PubChem ID | 5317284 | |
| Additional PMIDs | 34015367 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:225778-1 | |
| Safety | NA |