| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2181 | |
| Phytochemical name or plant extracts | Nepeta deflersiana | |
| PMID | 27013801 | |
| Literature evidence | Results showed that selected sub-fractions of the chloroform extract significantly reduced the cell viability of MCF-7 and A-549 cells, and altered the cellular morphology in a concentration-dependent manner. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Chloroform extract | |
| Source of phytochemicals or plant Extracts | Nepeta deflersiana | |
| Geographical availability | Saudi Arabia, Yemen | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The present study provides preliminary screening of anticancer activities of chloroform extract and sub-fractions of ND, which can be further used for the development of a potential therapeutic anticancer agent. | |
| Cell line/ mice model | MCF-7, A549 | |
| Additional information | Nepeta deflersiana extract exhibit cytotoxicity and altered the cellular morphology. Sub-fractions of the chloroform extract of Nepeta deflersiana reduced the cell viability of MCF-7 and A-549 cells. Among the sub-fractions, ND-10 fraction showed relatively higher cytotoxicity. The A-549 cells were found to be more sensitive as compared to the MCF-7 cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:900351-1 | |
| Safety | NA |