| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1958 | |
| Phytochemical name or plant extracts | Neotriptonoterpene | |
| PMID | 28098763 | |
| Literature evidence | The discovery of these twelve new diterpenes not only provided information on chemical substances of T. regelii, but also contributed to the chemical diversity of natural terpenoids. | |
| IUPAC name | (4aS,10aR)-6-hydroxy-8-methoxy-1,1,4a-trimethyl-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthren-2-one | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Tripterygium regelii | |
| Geographical availability | Japan, Korea, Manchuria | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Liver cancer, Ovarian cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 64.80 ± 24.90 µM against MCF-7 | |
| Potency | Compound 14 exhibited weak cytotoxic activity on A2780, HepG2, and MCF-7 cells with IC50 values of 65.80, 35.45, and 64.80 µM, respectively. Compound 14 is Neotriptonoterpene | |
| Cell line/ mice model | MCF-7, A2780, HepG2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:162907-1 | |
| Safety | NA |