| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-630 | |
| Phytochemical name or plant extracts | Myrtus communis essential oil | |
| PMID | 30661057 | |
| Literature evidence | Conclusions Myrtus communis L. essential oil exhibits a weak antioxidant effect, but induced remarkable cytotoxic activity by a mechanism related to apoptosis, suggesting a possible application of the bioactive compounds as natural anticancer compounds. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Myrtus communis | |
| Geographical availability | Afghanistan, Albania, Algeria, Azores, Baleares, Canary Is., Corse, Cyprus, East Aegean Is., Eritrea, Ethiopia, France, Greece, Iran, Iraq, Italy, Kriti, Lebanon-Syria, Libya, Madeira, Morocco, Ouazzane, Benslimane, Pakistan, Palestine, Portugal, Sardegna, Sicilia, Spain, Tunisia, Turkey, Yemen, Yugoslavia | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Myrtus communis essential oils from Ouazzane and Benslimane region respectively: 4 µg/mL against MCF-7 6.25 µg/mL against MCF-7 | |
| Potency | Myrtus communis L. essential oil exhibits a weak antioxidant effect, but induced remarkable cytotoxic activity by a mechanism related to apoptosis, suggesting a possible application of the bioactive compounds as natural anticancer compounds. | |
| Cell line/ mice model | MCF-7, P815 | |
| Additional information | Moreover, this cytotoxicity was partly associated with DNA fragmentation, which is one of the characteristics of apoptosis. The tested essential oils did not show strong antioxidant activity. | |
| PubChem ID | NA | |
| Additional PMIDs | 30661057 20942618 32328274 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:599719-1 | |
| Safety | NA |