| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-199 | |
| Phytochemical name or plant extracts | Momordica cochinchinensis extract | |
| PMID | 33238969 | |
| Literature evidence | This highlights the potential of this fruit in the development of novel anticancer agents against such tumours, with specific regions on where to collect the best variety and extraction solvent for optimum activity. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Aqueous extract | |
| Source of phytochemicals or plant Extracts | Momordica cochinchinensis | |
| Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, India, Jawa, Laos, Malaya, Maluku, Myanmar, New Guinea, Philippines, Queensland, Sulawesi, Sumatera, Taiwan, Thailand, Tibet, Vietnam | |
| Plant parts | Seed | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.59 mg/mL against MCF-7 | |
| Potency | The water extract of M. cochinchinensis aril caused significant apoptosis and necrosis of breast cancer and melanoma cells, with varieties from Northern Vietnam possessing superior activity. | |
| Cell line/ mice model | MCF-7, BT-474 | |
| Additional information | This highlights the potential of this fruit in the development of novel anticancer agents against such tumours, with specific regions on where to collect the best variety and extraction solvent for optimum activity. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:293419-1 | |
| Safety | NA |