Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-953 | |
Phytochemical name or plant extracts | Micranthin B | |
PMID | 23194512 | |
Literature evidence | Micranthin B (6) showed moderate activity against all the cells with IC(50) values of 16.29, 18.20, and 22.25 μM, while compounds 1-4 were inactive (IC(50)>50 μg/ml). | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Diterpenoid | |
Source of phytochemicals or plant Extracts | Isodon lophanthoides | |
Geographical availability | Assam, Bangladesh, China North-Central, China South-Central, China Southeast, East Himalaya, India, Laos, Malaya, Myanmar, Nepal, Thailand, Tibet, Vietnam, West Himalaya | |
Plant parts | Aerial parts | |
Other cancers | Breast cancer, Lung cancer, Cervical cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 18.20 μM against MCF-7 | |
Potency | Micranthin B (6) was cytotoxic towards human carcinoma A549, MCF-7, and HeLa cell lines, indicating that it could be involved in the antitumor activity of this plant. | |
Cell line/ mice model | MCF-7, A549, HeLa | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:915140-1 | |
Safety | NA |