Phytochemical Name : Methyl protoneodioscin (NSC-698791)

Properties Information
PhytoCAT-ID PhytoCAT-248
Phytochemical name or plant extracts Methyl protoneodioscin (NSC-698791)
PMID 12014616
Literature evidence Based on an analysis of COMPARE computer program with methyl protoneodioscin as a seed compound, no compounds in the NCIs anticancer drug screen database have similar cytotoxicity patterns (mean graphs) to that of methyl protoneodioscin, indicating a potential novel mechanism of anticancer action involved.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Saponin
Source of phytochemicals or plant Extracts Dioscorea collettii
Geographical availability China South-Central, China Southeast, Laos, Myanmar, Taiwan, Thailand, Vietnam
Plant parts Rhizome
Other cancers Breast cancer, Cervical cancer, Kidney cancer, Lung cancer, Colon cancer, Skin cancer, Prostate cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency NA
Cell line/ mice model A549, HCT-116, SF-539, SNB-75, M14, CAKI-1, DU-145, HS 578T, MDA-MB-435
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:317817-1
Safety NA