Properties |
Information |
PhytoCAT-ID |
PhytoCAT-1785 |
Phytochemical name or plant extracts |
Methyl antcinate B |
PMID |
22753732 |
Literature evidence |
In addition to MAA, methyl antcinate B, dehydroeburicoic acid, and 15α-acetyl-dehydrosulfurenic acid also exhibited significant selective cytotoxic effects to respective cancer cells. |
IUPAC name |
methyl (6R)-2-methyl-3-methylidene-6-[(4S,10S,13R,14R,17R)-4,10,13-trimethyl-3,7,11-trioxo-1,2,4,5,6,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]heptanoate |
Phytochemicals’ class or type of plant extracts |
Triterpenoid |
Source of phytochemicals or plant Extracts |
Antrodia camphorata, Antrodia cinnamomea |
|
Geographical availability |
Taiwan |
Plant parts |
NA |
Other cancers |
Breast cancer, Oral cancer, Epithelioid cancer, Prostate cancer, Ovarian cancer, Cervical cancer, Bone cancer, Stomach cancer |
Target gene or protein |
NA |
Gene or Protein evidence |
NA |
Target pathways |
NA |
IC50 |
>200 μM against BT-474
>200 μM against T47D |
Potency |
NA |
Cell line/ mice model |
KB, TSCCa, GNM, OC-2, and OEC-M1 , Panc-1 , BT-474, PC-3, OVCAR-3, HeLa, U2OS, ER+ T47D |
Additional information |
Exhibits significant selective cytotoxic effects on the cell lines |
PubChem ID |
53319129 |
Additional PMIDs |
NA |
Additional sources of information |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095428/ |
Safety |
NA |