Phytochemical Name : Methyl antcinate B

Properties Information
PhytoCAT-ID PhytoCAT-1785
Phytochemical name or plant extracts Methyl antcinate B
PMID 22753732
Literature evidence In addition to MAA, methyl antcinate B, dehydroeburicoic acid, and 15α-acetyl-dehydrosulfurenic acid also exhibited significant selective cytotoxic effects to respective cancer cells.
IUPAC name methyl (6R)-2-methyl-3-methylidene-6-[(4S,10S,13R,14R,17R)-4,10,13-trimethyl-3,7,11-trioxo-1,2,4,5,6,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]heptanoate
Phytochemicals’ class or type of plant extracts Triterpenoid
Source of phytochemicals or plant Extracts Antrodia camphorata, Antrodia cinnamomea
Geographical availability Taiwan
Plant parts NA
Other cancers Breast cancer, Oral cancer, Epithelioid cancer, Prostate cancer, Ovarian cancer, Cervical cancer, Bone cancer, Stomach cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 >200 μM against BT-474 >200 μM against T47D
Potency NA
Cell line/ mice model KB, TSCCa, GNM, OC-2, and OEC-M1 , Panc-1 , BT-474, PC-3, OVCAR-3, HeLa, U2OS, ER+ T47D
Additional information  Exhibits significant selective cytotoxic effects on the cell lines
PubChem ID 53319129
Additional PMIDs NA
Additional sources of information https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095428/
Safety NA