| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1515 | |
| Phytochemical name or plant extracts | Merulin C | |
| PMID | 20411928 | |
| Literature evidence | Compounds 1 and 3 displayed significant cytotoxicity against human breast (BT474) and colon (SW620) cancer cell lines. | |
| IUPAC name | (1R,6S,9R,10S)-10-hydroxy-10-(hydroxymethyl)-2,2,6-trimethyl-7,8-dioxatricyclo[7.3.1.01,6]tridec-3-en-5-one | |
| Phytochemicals’ class or type of plant extracts | Chamigrane endoperoxide | |
| Source of phytochemicals or plant Extracts | Endophytic fungus of Xylocarpus granatum | |
| Geographical availability | Aldabra, Andaman Is., Bangladesh, Bismarck Archipelago, Borneo, Cambodia, Caroline Is., Comoros, Fiji, Hainan, India, Jawa, Kenya, KwaZulu-Natal, Lesser Sunda Is., Madagascar, Malaya, Maluku, Mozambique, Myanmar, New Caledonia, New Guinea, Nicobar Is., Philippines, Seychelles, Solomon Is., Somalia, Sri Lanka, Sulawesi, Sumatera, Tanzania, Thailand, Tonga, Vanuatu, Vietnam | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.57 µg/mL against BT-474 | |
| Potency | Compounds 1 and 3 displayed significant cytotoxicity against human breast (BT474) and colon (SW620) cancer cell lines. cOMPOUND 3 IS Merulin C | |
| Cell line/ mice model | BT-474, SW621 | |
| Additional information | NA | |
| PubChem ID | 46831718 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579970-1 | |
| Safety | NA |