| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1690 | |
| Phytochemical name or plant extracts | Meriandra dianthera essential oil (MDEO) | |
| PMID | 31336582 | |
| Literature evidence | MDEO demonstrated an interesting cytotoxic activity against all cancer cell lines with IC50 values of 83.6 to 91.2 μg/mL, especially against MCF-7 cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Meriandra dianthera | |
| Geographical availability | Eritrea, Ethiopia, India, Saudi Arabia, Yemen | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 83.6 ± 0.6 µg/mL against MCF-7 | |
| Potency | At 24 h of treatment, MDEO induced apoptosis to the treated MCF-7 cell lines. There was no apoptosis (0%) in the untreated cells, indicating that the treatment with the essential oil caused induction of apoptosis. | |
| Cell line/ mice model | MCF-7, LOVO | |
| Additional information | Thus, our results support the hypothesis that MDEO could be a promising cytotoxic and antimicrobial agent. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:451358-1 | |
| Safety | NA |