| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-390 | |
| Phytochemical name or plant extracts | Melissa officinalis extract | |
| PMID | 26320439 | |
| Literature evidence | CONCLUSIONS: Our results indicate that a hydro-alcoholic extract of MO possess a high potency to inhibit proliferation of different tumor cells in a dose independent manner, suggesting that an optimal biological dose is more important than a maximally tolerated one. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hydro-alcoholic extract | |
| Source of phytochemicals or plant Extracts | Melissa officinalis | |
| Geographical availability | Albania, Algeria, Baleares, Bulgaria, Corse, Cyprus, East Aegean Is., France, Greece, Iran, Iraq, Italy, Kirgizstan, Kriti, Lebanon-Syria, Morocco, North Caucasus, Palestine, Portugal, Sardegna, Sicilia, Spain, Tadzhikistan, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Turkmenistan, Uzbekistan, Yugoslavia | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Ovarian cancer, Lung cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | <5 μg/ml against MCF-7 | |
| Potency | In all cancer cells, MOE reduced the cell viability to values below 33%, even at the lowest doses. | |
| Cell line/ mice model | SKOV3, MCF-7 and PC-3, A549 | |
| Additional information | The mean growth inhibition was 73.1%, 86.7%, 79.9% and 77.8% in SKOV3, MCF-7 and PC-3 and A549 cells, respectively. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:450084-1 | |
| Safety | NA |