| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-413 | |
| Phytochemical name or plant extracts | Maslinic acid | |
| PMID | 34365127 | |
| Literature evidence | Our findings suggest that the sulfamate derivative of maslinic acid MSBA-S might be a new option for the radiation therapy in breast cancer cells. | |
| IUPAC name | (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Salvia tomentosa | |
| Geographical availability | Albania, Bulgaria, East Aegean Is., Greece, Krym, Lebanon-Syria, Transcaucasus, Turkey, Turkey-in-Europe, Yugoslavia | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Between 3.7 μM and 5.8 μM | |
| Potency | In addition, MSBA-S in combination with irradiation resulted in effects on radiosensitivity in MDA-MB-231 cells (DMF10 = 1.14). | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | In particular, ROS formation was strongly assessed in MSBA-S-treated breast cancer cells. Our findings suggest that the sulfamate derivative of maslinic acid MSBA-S might be a new option for the radiation therapy in breast cancer cells. | |
| PubChem ID | 73659 | |
| Additional PMIDs | 28729623 19809970 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:457406-1 | |
| Safety | NA |