| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-874 | |
| Phytochemical name or plant extracts | Mansorin III | |
| PMID | 29701706 | |
| Literature evidence | Mansorin-B and mansonone-G were found to inhibit the P-gp attached ATPase subunit. | |
| IUPAC name | (8R)-8-hydroxy-4,8,12-trimethyl-2,6-dioxatricyclo[7.3.1.05,13]trideca-1(12),4,9(13),10-tetraen-3-one | |
| Phytochemicals’ class or type of plant extracts | Coumarin | |
| Source of phytochemicals or plant Extracts | Mansonia gagei | |
| Geographical availability | Laos, Myanmar, Thailand | |
| Plant parts | Heartwood | |
| Other cancers | Breast cancer, Cervical cancer, Colorectal cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >100 µM against MCF-7 | |
| Potency | On the other hand, mansorin-A, mansorin-C and mansorin III suffered from high cellular resistance in HepG2 cells (R-values were higher than 30%). | |
| Cell line/ mice model | MCF-7, HepG2, HCT-116, HeLa | |
| Additional information | NA | |
| PubChem ID | 23651870 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:824303-1 | |
| Safety | NA |