| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1918 | |
| Phytochemical name or plant extracts | Mangostanaxanthone VII | |
| PMID | 29116938 | |
| Literature evidence | Mangostanaxanthone VII showed moderate cytotoxic activity against the A549 and MCF7 cell lines with IC50s 26.1 and 34.8 μM, respectively, compared with doxorubicin (0.74 and 0.41 μM, respectively). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Xanthone | |
| Source of phytochemicals or plant Extracts | Garcinia mangostana | |
| Geographical availability | Borneo, Malaya | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 34.8 μM against MCF-7 | |
| Potency | Compound 5 showed moderate cytotoxic activity against the A549 and MCF7 cell lines with IC50 values of 26.1 and 34.8 μM, respectively, compared with doxorubicin (0.74 and 0.41 μM, respectively). Compound 5 is Mangostanaxanthone VII | |
| Cell line/ mice model | A549, MCF-7 | |
| Additional information | However, it exhibited no any antimicrobial activity towards the tested strains. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:428073-1 | |
| Safety | NA |