Properties | Information |
---|---|
PhytoCAT-ID | PhytoCAT-1740 |
Phytochemical name or plant extracts | Malabaricone C (mal C) |
PMID | 20805034 |
Literature evidence | The inactivity of malabaricone A and malabaricone D revealed that the resorcinol moiety, present in the malabaricones did not contribute to the nuclease activity. |
IUPAC name | 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one |
Phytochemicals’ class or type of plant extracts | Butanone |
Source of phytochemicals or plant Extracts | NA |
Geographical availability | NA |
Plant parts | NA |
Other cancers | Breast cancer |
Target gene or protein | NA |
Gene or Protein evidence | NA |
Target pathways | Apoptotic pathway involving oxidative damage to the cellular DNA. |
IC50 | 5.26±1.20 μM against MCF-7 |
Potency | Considering this, and the encouraging present findings, mal C appears to be a potential anti-cancer agent for further evaluation. |
Cell line/ mice model | MCF-7 |
Additional information | NA |
PubChem ID | 100313 |
Additional PMIDs | NA |
Additional sources of information | NA |
Safety | NA |