Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-861 | |
Phytochemical name or plant extracts | Lycium barbarum polysaccharides(LBGP-I-3) | |
PMID | 31991207 | |
Literature evidence | LBGP-I-3 arrested the cell cycle at the G0/G1 phase, altered mitochondrial function, activated oxidative stress, and regulated the MAPK signaling pathway to induce apoptosis. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Arabinogalactan | |
Source of phytochemicals or plant Extracts | Lycium barbarum | |
Geographical availability | China North-Central, China South-Central, Inner Mongolia, Qinghai, Xinjiang | |
Plant parts | Fruits | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | MAPK signaling pathway | |
IC50 | NA | |
Potency | LBGP-I-3 arrested the cell cycle at the G0/G1 phase, altered mitochondrial function, activated oxidative stress, and regulated the MAPK signaling pathway to induce apoptosis. | |
Cell line/ mice model | MCF-7 | |
Additional information | LBGP-I-3 may be a potential functional food ingredient for the prevention of cancer without toxicity to normal cells in vitro. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:816356-1 | |
Safety | NA |