Phytochemical Name : Lycium barbarum polysaccharides(LBGP-I-3)

Properties Information
PhytoCAT-ID PhytoCAT-861
Phytochemical name or plant extracts Lycium barbarum polysaccharides(LBGP-I-3)
PMID 31991207
Literature evidence LBGP-I-3 arrested the cell cycle at the G0/G1 phase, altered mitochondrial function, activated oxidative stress, and regulated the MAPK signaling pathway to induce apoptosis.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Arabinogalactan
Source of phytochemicals or plant Extracts Lycium barbarum
Geographical availability China North-Central, China South-Central, Inner Mongolia, Qinghai, Xinjiang
Plant parts Fruits
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways MAPK signaling pathway
IC50 NA
Potency LBGP-I-3 arrested the cell cycle at the G0/G1 phase, altered mitochondrial function, activated oxidative stress, and regulated the MAPK signaling pathway to induce apoptosis.
Cell line/ mice model MCF-7
Additional information  LBGP-I-3 may be a potential functional food ingredient for the prevention of cancer without toxicity to normal cells in vitro.
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:816356-1
Safety NA