| Properties | Information |
|---|---|
| PhytoCAT-ID | PhytoCAT-1673 |
| Phytochemical name or plant extracts | Luteolin and its oxidovanadium(IV) complex [VO(lut)(H2O)2]Na·3H2O (VOlut) |
| PMID | 27707626 |
| Literature evidence | Considering that the complex displayed strong anticancer activity on MDAMB231 human breast cancer cell line we herein determined through in vitro assays that the complex would probably reduce breast cancer cell metastasis in a higher extent than the natural antioxidant. |
| IUPAC name | NA |
| Phytochemicals’ class or type of plant extracts | Complex |
| Source of phytochemicals or plant Extracts | NA |
| Geographical availability | NA |
| Plant parts | NA |
| Other cancers | Breast cancer, Colon cancer, Lung cancer |
| Target gene or protein | NA |
| Gene or Protein evidence | NA |
| Target pathways | NA |
| IC50 | 88.3 μM to 17.0 μM against MDA-MB-231 |
| Potency | Considering that the complex displayed strong anticancer activity on MDAMB231 human breast cancer cell line we herein determined through in vitro assays that the complex would probably reduce breast cancer cell metastasis in a higher extent than the natural antioxidant. |
| Cell line/ mice model | MDA-MB-231, CT26, A549, Balb/C mice |
| Additional information | Working with a murine model of highly aggressive, orthotopic colon cancer model (CT26 cancer cell lines) it has been determined that the complex might prevent metastatic dissemination of the colon cancer cells to the liver. |
| PubChem ID | NA |
| Additional PMIDs | 26828287 |
| Additional sources of information | NA |
| Safety | NA |