| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1457 | |
| Phytochemical name or plant extracts | Lupinalbin D | |
| PMID | 34038794 | |
| Literature evidence | Meanwhile, compounds 5 and 12 exhibited significant inhibition activities on NO production in LPS-stimulated RAW 264.7 cell line compared with positive control indometacin. | |
| IUPAC name | 1,3,8-trihydroxy-7-(3-methylbut-2-enyl)-[1]benzofuro[2,3-b]chromen-11-one | |
| Phytochemicals’ class or type of plant extracts | Prenylated coumaronochromone | |
| Source of phytochemicals or plant Extracts | Ficus altissima | |
| Geographical availability | Andaman Is., Assam, Bangladesh, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Malaya, Myanmar, Nepal, Nicobar Is., Philippines, Sri Lanka, Sulawesi, Sumatera, Thailand, Vietnam | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 35.31 ± 2.75 µM against MDA-MB-231 98.84 ± 0.75 µM against MCF-7 | |
| Potency | Compounds 3 and 16 exhibited obvious anti-proliferative activities and relatively high selectivity index against HepG2 and MDA-MB-231 cell lines. Compound 3 is Lupinalbin D. | |
| Cell line/ mice model | HepG2, MCF-7, MDA-MB-231 | |
| Additional information | NA | |
| PubChem ID | 44260099 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:852369-1 | |
| Safety | NA |