| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-890 | |
| Phytochemical name or plant extracts | Luehea candicans extract | |
| PMID | 21432719 | |
| Literature evidence | The crude methanolic extracts from the branches (B) and leaves (L) were able to inhibit the growth of the K-562 and 786-0 cell lines in a dose-dependent manner, with GI(50) values of 8.1 and 5.4 µg mL(-1), respectively. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Luehea candicans | |
| Geographical availability | Argentina Northeast, Bolivia, Brazil South, Brazil Southeast, Brazil West-Central, Paraguay | |
| Plant parts | Branches, Leaves | |
| Other cancers | Breast cancer, Lung cancer, Kidney cancer, Prostate cancer, Ovarian cancer, Colon cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The chloroform (B2) and methanol (B3) fractions derived from extract (B) exhibited less selectivity, showing the highest cytostatic activity against K-562, NCI-ADR, OVCAR, MCF-7 and NCI-460 cells, with GI(50) values between 27 and 40 µg mL(-1). | |
| Cell line/ mice model | MCF-7, NCI-ADR, NCI-460, UACC-62, 786-0, OVCAR, PCO-3, HT-29, K-562 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:834726-1 | |
| Safety | NA |