| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1734 | |
| Phytochemical name or plant extracts | Loquat extract | |
| PMID | 20098577 | |
| Literature evidence | Our results indicate that methanol extracts of loquat inhibit the adhesion, migration and invasion of human breast cancer cells partially through the inhibition of MMP activity and leaf extract has more anti-metastatic effects in cell based assay than seed extract. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Eriobotrya japonica | |
| Geographical availability | China South-Central | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Clinical application of loquat extract as a potent chemopreventive agent may be helpful in limiting breast cancer invasion and metastasis. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | Loquat leaf extract was more effective than seed extract on the inhibition of proliferation, adhesion, invasion, and MMP activities in the MDA-MB-231 cells | |
| PubChem ID | NA | |
| Additional PMIDs | 27087896 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:724793-1 | |
| Safety | NA |