Phytochemical Name : Licoagrochalcone B

Properties Information
PhytoCAT-ID PhytoCAT-651
Phytochemical name or plant extracts Licoagrochalcone B
PMID 16545824
Literature evidence Subsequently, their anticancer activities were also examined to inhibit human cancer cells' growth including A549, BEL-7402, SGC-7901, MCF-7, HT-29, K562 and A498 cell lines by MTT method in vitro.
IUPAC name (E)-1-(4-hydroxyphenyl)-3-(5-methoxy-2,2-dimethylchromen-6-yl)prop-2-en-1-one
Phytochemicals’ class or type of plant extracts Chalcone
Source of phytochemicals or plant Extracts Patrinia villosa
Geographical availability China South-Central, China Southeast, Japan, Korea, Manchuria, Nansei-shoto, Taiwan, Vietnam
Plant parts Leaves
Other cancers Breast cancer, Liver cancer, Lung cancer, esophageal cancer, Stomach cancer, Leukemia, Kidney cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 28.54 µg/ml against MCF-7
Potency The compounds 4, 5 and 6 exhibited weaker inhibition effect (IC50 < 30 microg/ml).
Cell line/ mice model MCF-7, BEL-7402, HT-29, SGC-7901, K562, A498, A549
Additional information  NA
PubChem ID 5318989
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:60452696-2
Safety NA