| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1660 | |
| Phytochemical name or plant extracts | Leucobryum bowringii extract | |
| PMID | 23140017 | |
| Literature evidence | The results indicate that methanol extracts inhibit the growth of human breast cancer cells partially through the inhibition of metallo proteinases MMP-2 and MMP-9 activities. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Leucobryum bowringii Mitt | |
| Geographical availability | NA | |
| Plant parts | Moss | |
| Other cancers | Breast cancer | |
| Target gene or protein | MMP2, MMP9 | |
| Gene or Protein evidence | The results indicate that methanol extracts inhibit the growth of human breast cancer cells partially through the inhibition of metallo proteinases MMP-2 and MMP-9 activities. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Methanolic extract has more anti-metastatic effects in cell based assay than water extract. Clinical application of L. bowringii extract as a bioactive chemopreventive compound may be helpful in limiting breast carcinoma invasion and metastasis. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |