| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-684 | |
| Phytochemical name or plant extracts | Leptopidine | |
| PMID | 26544947 | |
| Literature evidence | These results suggest that leptopidine could suppress growth and induce cytotoxicity in breast cancer cells and that the cytotoxicity of leptopidine may be related to its inhibitory effect on fatty acid synthase expression. © 2015 WILEY-VCH Verlag GmbH & Co. | |
| IUPAC name | 2-hydroxy-3-methoxy-6-[(6-methyl-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl)methyl]benzoic acid | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Hypecoum leptocarpum | |
| Geographical availability | Afghanistan, China North-Central, China South-Central, East Himalaya, Inner Mongolia, Mongolia, Nepal, Pakistan, Qinghai, Tadzhikistan, Tibet, West Himalaya, Xinjiang | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | FAS | |
| Gene or Protein evidence | These results suggest that leptopidine could suppress growth and induce cytotoxicity in breast cancer cells and that the cytotoxicity of leptopidine may be related to its inhibitory effect on fatty acid synthase expression. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | These results suggest that leptopidine could suppress growth and induce cytotoxicity in breast cancer cells and that the cytotoxicity of leptopidine may be related to its inhibitory effect on fatty acid synthase expression. | |
| Cell line/ mice model | NA | |
| Additional information | NA | |
| PubChem ID | 5318973 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:673242-1 | |
| Safety | NA |