| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-999 | |
| Phytochemical name or plant extracts | Leptadenia pyrotechnica extract | |
| PMID | 21894086 | |
| Literature evidence | The total antioxidant capacity was estimated by the FRAP, DPPH, ABTS and β-carotene bleaching assays.The ethyl acetate fraction exhibited the highest polyphenolic content (252.27 mg gallic acid/g) and the best antioxidant activity (1.2, 0.57, 0.45 mmol ascorbic acid equivalent/g in the FRAP, ABTS and DPPH assays, respectively). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Aqueous Ethanolic crude extract | |
| Source of phytochemicals or plant Extracts | Leptadenia pyrotechnica | |
| Geographical availability | Algeria, Burkina, Cameroon, Chad, Djibouti, Egypt, Eritrea, Ethiopia, Gulf States, India, Iran, Libya, Mali, Mauritania, Morocco, Niger, Nigeria, Oman, Pakistan, Palestine, Saudi Arabia, Senegal, Sinai, Somalia, Sudan, Yemen | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 43.16 µg/mL against MCF-7 | |
| Potency | These results suggest that this plant may be considered an interesting source of compounds with antioxidant, anti-inflammatory and anti-cancer properties for therapeutic, nutraceutical and functional food applications. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Furthermore, the same extract showed appreciable anti-inflammatory via lipoxygenase (LOX) inhibitory activity (IC₅₀ = 1.41 µg/mL). | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:98980-1 | |
| Safety | NA |