| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1130 | |
| Phytochemical name or plant extracts | Lawsonia inermis extract | |
| PMID | 28337113 | |
| Literature evidence | HPLC profiling of W-LI revealed the presence of different polyphenolic compounds such as ellagic acid, catechin, quercetin, kaempferol etc. which might be contributing towards antioxidant and cytotoxic activity. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Aqueous extract | |
| Source of phytochemicals or plant Extracts | Lawsonia inermis | |
| Geographical availability | Djibouti, Eritrea, Ethiopia, India, Kenya, Oman, Pakistan, Panamá, Saudi Arabia, Somalia, Tanzania, Yemen | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Lung cancer, Cervical cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | W-LI was found to be promising inhibitor of both DPPH and ABTS cation radicals with an IC50 of 352.77 and 380.87 µg/ml respectively. | |
| Potency | The present study demonstrated that polyphenols rich W-LI extract from leaves of L. inermis possesses ability to inhibit oxidative radicals and cancer cells proliferation. | |
| Cell line/ mice model | MCF-7, A549, C6 and COLO-205 | |
| Additional information | However, extract showed promising growth inhibitory activity against COLO 205 cells with GI50 of 121.03 g/ml. | |
| PubChem ID | NA | |
| Additional PMIDs | 28476954 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:553638-1 | |
| Safety | NA |