| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-940 | |
| Phytochemical name or plant extracts | Larrea tridentata extract | |
| PMID | 17487409 | |
| Literature evidence | Plants used in folklore medicine continue to be an important source of discovery and development of novel therapeutic agents. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Aqueous extract | |
| Source of phytochemicals or plant Extracts | Larrea tridentata | |
| Geographical availability | Arizona, California, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southwest, Nevada, New Mexico, Texas, Utah | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | ERK1/2 | |
| Gene or Protein evidence | Furthermore, the phosphorylation levels of extracellular signal-regulated kinase 1 and 2 (ERK1/2) decreased when the cells were exposed to aqueous extracts of L. tridentata, J. communis L. and A. californica. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Our results showed that extracts of L. tridentata (Creosote Bush) and J. communis L. (Juniper Berry) significantly decreased the growth of MCF-7/AZ breast cancer cells. | |
| Cell line/ mice model | MCF-7/AZ | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:873322-1 | |
| Safety | NA |