| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-278 | |
| Phytochemical name or plant extracts | Laevifins B | |
| PMID | 30316148 | |
| Literature evidence | In vitro cytotoxicity assays on laevifins A, B and G showed moderate activities against the MCF-7 cancer cell line (IC50 102, 115 and 106 μM, respectively) while β-amyrin and acetyl aleuritolic acid showed good anti-inflammatory activity on the LPS-induced NF-κB translocation inhibition in RAW 264.7 cells assay with IC50 values of 23.5 and 35.4 μg/mL, respectively. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Croton oblongus | |
| Geographical availability | Borneo, Jawa, Lesser Sunda Is., Sulawesi, Sumatera | |
| Plant parts | Stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 115 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:343110-1 | |
| Safety | NA |