| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-547 | |
| Phytochemical name or plant extracts | Kwanzoquinones E | |
| PMID | 14741736 | |
| Literature evidence | Daylilies (Hemerocallis) are used medicinally in eastern Asia and extracts of the plant had been shown to inhibit cell proliferation and induce cancer cells to undergo differentiation. | |
| IUPAC name | 1,2,8-trihydroxy-3-(hydroxymethyl)anthracene-9,10-dione | |
| Phytochemicals’ class or type of plant extracts | Quinone | |
| Source of phytochemicals or plant Extracts | Hemerocallis fulva | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Japan, Korea, Nansei-shoto, Taiwan | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Brain cancer, Colon cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Kwanzoquinones A-C and E, kwanzoquinone A and B monoacetates (1a and 2a), 2-hydroxychrysophanol, and rhein inhibited the proliferation of human breast, CNS, colon, and lung cancer cells with GI50 values between 1.8 to 21.1 microg/mL. | |
| Cell line/ mice model | NA | |
| Additional information | NA | |
| PubChem ID | 10125440 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:536335-2 | |
| Safety | NA |