Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1679 | |
Phytochemical name or plant extracts | Kuwanon C | |
PMID | 30822142 | |
Literature evidence | Antiproliferative activity of stilbene derivatives and other constituents from the stem bark of Morus nigra L. | |
IUPAC name | 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methylbut-2-enyl)chromen-4-one | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Morus nigra | |
Geographical availability | Iran | |
Plant parts | Barks | |
Other cancers | Breast cancer, Liver cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 3.92 μM against MCF-7 | |
Potency | However, kuwanon C (5) showed the highest antiproliferative activity with IC50 3.92 and 9.54 μM against MCF-7 and HepG2, respectively. | |
Cell line/ mice model | MCF-7, HepG2 | |
Additional information | NA | |
PubChem ID | 5481958 | |
Additional PMIDs | 30822142 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:854688-1 | |
Safety | NA |