| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1480 | |
| Phytochemical name or plant extracts | Kopsifoline K | |
| PMID | 29935259 | |
| Literature evidence | Alkaloids 3-5 also possessed significant antimicrobial and antifungal activities which was reported for the first time for the alkaloids isolated from Kopsia genus. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Kopsia fruticosa | |
| Geographical availability | Andaman Is., Myanmar | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Skin cancer, Stomach cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 8.6 µM against MCF-7 | |
| Potency | As a result, alkaloids 3-5 exhibited some cytotoxicity against all of seven tested tumor cell lines (HS-1, HS-4, SCL-1, A431, BGC-823, MCF-7, and W480) with IC50 values of 11.8-13.8, 10.3-12.5, and 7.3-9.5 ?M, respectively. Alkaloid 5 is Kopsifoline K | |
| Cell line/ mice model | HS-1, HS-4, SCL-1, A431, BGC-823, MCF-7, and W480 | |
| Additional information | Alkaloids 3-5 also possessed significant antimicrobial and antifungal activities which was reported for the first time for the alkaloids isolated from Kopsia genus. Alkaloid 5 is Kopsifoline K | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:79497-1 | |
| Safety | NA |