| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-560 | |
| Phytochemical name or plant extracts | Kaempferol-7 glucoside | |
| PMID | 24711053 | |
| Literature evidence | In addition, the extract exhibited promising analgesic, antipyretic as well as anti-inflammatory activities. | |
| IUPAC name | 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Strychnos nux-vomica | |
| Geographical availability | Bangladesh, Cambodia, India, Laos, Malaya, Myanmar, Sri Lanka, Thailand, Vietnam | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Larynx cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The extract showed potential cytotoxic activity against human epidermoid larynx carcinoma cells (Hep-2) and against breast carcinoma cell line (MCF-7). | |
| Cell line/ mice model | MCF-7, Hep-2, HCT | |
| Additional information | It is concluded that, leaves extract of S. nux vomica possess potent cytotoxic, analgesic, antipyretic and anti-inflammatory activities. These activities could be due to the presence of phenolic compounds revealed by our phytochemical investigations. | |
| PubChem ID | 10095180 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:547371-1 | |
| Safety | NA |