Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1575 | |
Phytochemical name or plant extracts | Kaempferol-3-O-methyl ether | |
PMID | 17335117 | |
Literature evidence | The P-gp inhibitory activity of these two compounds was through a 3-fold increase of the level of [(3)H]-DNM accumulation and a decrease of P-gp-mediated efflux. | |
IUPAC name | 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxychromen-4-one | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Zingiber zerumbet | |
Geographical availability | Andaman Is., Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, India, Laos, Malaya, Myanmar, Nicobar Is., Philippines, Taiwan, Thailand, Vietnam | |
Plant parts | Rhizome | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 14.6 ± 2.9 µM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | 5280862 | |
Additional PMIDs | 27462359 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:798401-1 | |
Safety | NA |