Phytochemical Name : Kaempferol-3-O-glucuronide

Properties Information
PhytoCAT-ID PhytoCAT-707
Phytochemical name or plant extracts Kaempferol-3-O-glucuronide
PMID 26922854
Literature evidence Quercetin showed significant cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 4.88 and 0.87 μg/mL, respectively.
IUPAC name 6-[3,5-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Calligonum polygonoides
Geographical availability Gulf States, Iran, Iraq, Kuwait, Lebanon-Syria, Pakistan, Palestine, Saudi Arabia, Sinai, Transcaucasus, Turkey, Yemen
Plant parts Aerial parts
Other cancers Breast cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 33.23 µg/ml against MCF-7
Potency NA
Cell line/ mice model MCF-7, HepG2
Additional information  K3O exhibited a reduction in oxidative stress and lipid peroxidation, and this may be related to the Nrf2/Keap1 pathway in the NAFLD larval zebrafish model.
PubChem ID 74315888
Additional PMIDs 34069176
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:693386-1
Safety NA