Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-707 | |
Phytochemical name or plant extracts | Kaempferol-3-O-glucuronide | |
PMID | 26922854 | |
Literature evidence | Quercetin showed significant cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 4.88 and 0.87 μg/mL, respectively. | |
IUPAC name | 6-[3,5-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Calligonum polygonoides | |
Geographical availability | Gulf States, Iran, Iraq, Kuwait, Lebanon-Syria, Pakistan, Palestine, Saudi Arabia, Sinai, Transcaucasus, Turkey, Yemen | |
Plant parts | Aerial parts | |
Other cancers | Breast cancer, Liver cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 33.23 µg/ml against MCF-7 | |
Potency | NA | |
Cell line/ mice model | MCF-7, HepG2 | |
Additional information | K3O exhibited a reduction in oxidative stress and lipid peroxidation, and this may be related to the Nrf2/Keap1 pathway in the NAFLD larval zebrafish model. | |
PubChem ID | 74315888 | |
Additional PMIDs | 34069176 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:693386-1 | |
Safety | NA |