Phytochemical Name : Kaempferol-3,4' -O-dimethyl ether

Properties Information
PhytoCAT-ID PhytoCAT-1576
Phytochemical name or plant extracts Kaempferol-3,4' -O-dimethyl ether
PMID 17335117
Literature evidence The P-gp inhibitory activity of these two compounds was through a 3-fold increase of the level of [(3)H]-DNM accumulation and a decrease of P-gp-mediated efflux.
IUPAC name 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-6-(methoxymethyl)chromen-4-one
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Zingiber zerumbet
Geographical availability Andaman Is., Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, India, Laos, Malaya, Myanmar, Nicobar Is., Philippines, Taiwan, Thailand, Vietnam
Plant parts Rhizome
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 10.9 ± 2.2 µM against MCF-7
Potency NA
Cell line/ mice model MCF-7
Additional information  NA
PubChem ID 129825756
Additional PMIDs 27462359
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:798401-1
Safety NA