| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-12 | |
| Phytochemical name or plant extracts | Kaempferol 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside | |
| PMID | 28951762 | |
| Literature evidence | Ethanol extracts of the three parts of C. procera were evaluated for their antiulcer activity and we found that the leaf extract possessed a powerful antiulcer activity which could be considered as a promising drug candidate. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Flavonoid glycoside | |
| Source of phytochemicals or plant Extracts | Calotropis procera | |
| Geographical availability | Afghanistan, Algeria, Assam, Bangladesh, Benin, Burkina, Cambodia, Cameroon, Canary Is., Cape Verde, Central African Repu, Chad, Congo, Djibouti, East Himalaya, Egypt, Eritrea, Ethiopia, Gambia, Ghana, Guinea, Guinea-Bissau, Gulf of Guinea Is., Gulf States, India, Iran, Ivory Coast, Kenya, Kuwait, Lebanon-Syria, Libya, Malawi, Mali, Mauritania, Morocco, Mozambique, Myanmar, Nepal, Niger, Nigeria, Oman, Pakistan, Palestine, Saudi Arabia, Senegal, Sierra Leone, Sinai, Socotra, Somalia, Sudan, Tanzania, Thailand, Tunisia, Uganda, Vietnam, Western Sahara, Yemen, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Colorectal cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 18.0 ± 3.40 µg/mL against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, HCT-116, HepG-2, A-549, SK-LU-1, KB | |
| Additional information | Compound 2 was highly active on all the cell lines, whereas compounds 5 and 11 were more selective on colon and liver cell lines. Compound 10 demonstrated a significant activity on liver and lung cancer cell lines. Compound 11 is Kaempferol 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:1004515-2 | |
| Safety | NA |