Phytochemical Name : Juniperus communis L. extract

Properties Information
PhytoCAT-ID PhytoCAT-215
Phytochemical name or plant extracts Juniperus communis L. extract
PMID 17487409
Literature evidence Plants used in folklore medicine continue to be an important source of discovery and development of novel therapeutic agents.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Aqueous extract
Source of phytochemicals or plant Extracts Juniperus communis
Geographical availability Afghanistan, Alabama, Alaska, Albania, Algeria, Altay, Amur, Arizona, Austria, Baltic States, Belarus, Belgium, British Columbia, Bulgaria, Buryatiya, California, Central European Rus, Chita, Colorado, Connecticut, Corse, Cyprus, Czechoslovakia, Denmark, East Aegean Is., East European Russia, Finland, France, Føroyar, Georgia, Germany, Great Britain, Greece, Greenland, Hungary, Iceland, Idaho, Illinois, Indiana, Inner Mongolia, Iowa, Iran, Iraq, Ireland, Irkutsk, Italy, Japan, Kamchatka, Kazakhstan, Kentucky, Khabarovsk, Kirgizstan, Korea, Krasnoyarsk, Krym, Kuril Is., Labrador, Lebanon-Syria, Magadan, Maine, Manchuria, Maryland, Massachusetts, Michigan, Minnesota, Mongolia, Montana, Morocco, Nebraska, Nepal, Netherlands, Nevada, New Brunswick, New Hampshire, New Jersey, New Mexico, New York, Newfoundland, North Carolina, North Caucasus, North Dakota, North European Russi, Northwest European R, Northwest Territorie, Norway, Nova Scotia, Nunavut, Ohio, Ontario, Oregon, Pakistan, Pennsylvania, Poland, Portugal, Primorye, Prince Edward I., Québec, Rhode I., Romania, Sakhalin, Sardegna, Sicilia, South Carolina, South Dakota, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Tennessee, Transcaucasus, Turkey, Turkey-in-Europe, Turkmenistan, Tuva, Ukraine, Utah, Uzbekistan, Vermont, Virginia, Washington, West Himalaya, West Siberia, West Virginia, Wisconsin, Wyoming, Xinjiang, Yakutskiya, Yugoslavia, Yukon
Plant parts NA
Other cancers Breast cancer
Target gene or protein ERK1/3
Gene or Protein evidence Furthermore, the phosphorylation levels of extracellular signal-regulated kinase 1 and 2 (ERK1/2) decreased when the cells were exposed to aqueous extracts of L. tridentata, J. communis L. and A. californica.
Target pathways NA
IC50 NA
Potency Our results showed that extracts of L. tridentata (Creosote Bush) and J. communis L. (Juniper Berry) significantly decreased the growth of MCF-7/AZ breast cancer cells.
Cell line/ mice model MCF-7/AZ
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30088655-2
Safety NA