Phytochemical Name : Julibroside J19

Properties Information
PhytoCAT-ID PhytoCAT-1513
Phytochemical name or plant extracts Julibroside J19
PMID 16308192
Literature evidence Both compounds show significant inhibition action against HeLa, Bel-7402 and MDA-MB-435 cancer cell lines in vitro.
IUPAC name 3-O-[beta-D-xylopyranosyl-(1 --> 2)-beta-D-fucopyranosyl-(1 --> 6)-beta-D-2-deoxy-2-acetoamidoglucopyranosyl]-21-O-{(6S)-2-trans-2-hydroxymethyl-6-methyl-6-O-[4-O-((6S)-2-trans-2-hydroxymethyl-6-hydroxy-6-methyl-2,7-octadienoyl)-beta-D-quinovopyranosyl]-2,7-octadienoyl}-acacic acid-28-O-beta-D-glucopyranosyl-(1 --> 3)-[alpha-L-arabinofuranosyl-(1 --> 4)]-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranosyl ester
Phytochemicals’ class or type of plant extracts Saponin
Source of phytochemicals or plant Extracts Albizzia julibrissin Durazz
Geographical availability Assam, Bangladesh, China North-Central, China South-Central, China Southeast, East Himalaya, India, Iran, Japan, Korea, Myanmar, Nansei-shoto, Nepal, Pakistan, Taiwan, Tibet, Transcaucasus, West Himalaya
Plant parts Stem
Other cancers Breast cancer, Cervical cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency Both 1 and 2 show significant cytotoxicities against the cancer cell lines at 100 mg ml21 assayed by SRB method. Compound 1 is Julibroside J19
Cell line/ mice model HeLa, Bel-7402 and MDA-MB-435
Additional information  Shows significant cytotoxicity against HeLa, Bel-7402 and MDA-MB-435 cell lines
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:473275-1
Safety NA