| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1316 | |
| Phytochemical name or plant extracts | Juglone | |
| PMID | 27397432 | |
| Literature evidence | Compounds 1-4 exhibited significant cytotoxicity towards cultured MDA-MB231, HepG2 and SNU638 cells with IC50 values ranging from 4.46 to 88.47 μM. | |
| IUPAC name | 5-hydroxynaphthalene-1,4-dione | |
| Phytochemicals’ class or type of plant extracts | Quinone | |
| Source of phytochemicals or plant Extracts | Juglans mandshurica | |
| Geographical availability | Amur, China North-Central, China South-Central, China Southeast, Inner Mongolia, Japan, Khabarovsk, Korea, Kuril Is., Manchuria, Primorye, Sakhalin, Taiwan | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Stomach cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 4.46 µM against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | MDA-MB-231, HepG2, SNU638 | |
| Additional information | Exhibits significant cytotoxicity towards cultured MDA-MB231, HepG2 and SNU638 cells | |
| PubChem ID | 3806 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:442388-1 | |
| Safety | NA |