| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1161 | |
| Phytochemical name or plant extracts | Jaboticaba peel extract (JPE) | |
| PMID | 31242771 | |
| Literature evidence | The antioxidant activity toward 2,2-diphenyl-1-picrylhydrazyl (DPPH) performed IC50 = 37.45 ± 0.17 µg mL-1, whereas 45.7% of acetylcholinesterase activity was inhibited. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Plinia cauliflora | |
| Geographical availability | Bolivia, Brazil Northeast, Brazil South, Brazil Southeast | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | JPE had moderate toxicity (LD50 = 360.92 μg mL-1) on A. salina, non-toxic effect on L929 cell line, and decreased the viability of cancer cell line MDA at 1,000 µg mL-1 and 500 µg mL-1 concentrations. | |
| Cell line/ mice model | MDA-MB-231, L929 | |
| Additional information | The JPE treatment resulted in cytokine-cytokine receptor interaction activation mostly by up regulating pro-inflammatory, pro-angiogenic, immunostimulatory and immunosuppressive genes. | |
| PubChem ID | NA | |
| Additional PMIDs | 36258714 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:203847-2 | |
| Safety | NA |