| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1681 | |
| Phytochemical name or plant extracts | Isoforrethin-D | |
| PMID | 30825576 | |
| Literature evidence | All of these compounds were evaluated for their cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and compound 4 showed significant inhibitory activities against SMMC-7721, A-549, MCF-7, and SW-480. | |
| IUPAC name | (3aR,5aS,6R,9aR,9bS,11aS)-6-(hydroxymethyl)-6,9a-dimethyl-1-methylidene-1H,2H,3aH,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-phenanthro[1,2-b]furan-2-one | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Isodon forrestii var forrestii | |
| Geographical availability | China South-Central | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Colon cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 16.6 ± 0.3 μM against MCF-7 | |
| Potency | Shows significant inhibitory activities against SMMC-7721, A-549, MCF-7, and SW-480. | |
| Cell line/ mice model | SMMC-7721, A-549, MCF-7, SW-480 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:448576-1 | |
| Safety | NA |