| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-928 | |
| Phytochemical name or plant extracts | Icetexane-1 | |
| PMID | 19700323 | |
| Literature evidence | Compounds 1 and 3 showed selective inhibitory activity against MCF-7 (15.96microg/mL and 15.84microg/mL) and HT-29 cell lines (16.21microg/mL and 14.57microg/mL), respectively. | |
| IUPAC name | 8,11,13 icetexatriene-10,11,12,16-tetrol | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Premna tomentosa | |
| Geographical availability | Andaman Is., Assam, Bangladesh, Borneo, Cambodia, East Himalaya, India, Jawa, Malaya, Myanmar, Nepal, Nicobar Is., Philippines, Queensland, Solomon Is., Sri Lanka, Sulawesi, Sumatera, Thailand, Vietnam | |
| Plant parts | Stem-Bark | |
| Other cancers | Breast cancer, Colon cancer, Skin cancer, Liver cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 15.96 ± 0.21 μg/mL against MCF-7 | |
| Potency | It was found that compounds 1 and 3 are showing potent activity against A-549 (lung cancer) HT-29 (colon cancer), and MCF-7 (breast cancer) cell lines. | |
| Cell line/ mice model | MCF-7, HT-29, Hep-G2, A-431, and A-549 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:864460-1 | |
| Safety | NA |