| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1677 | |
| Phytochemical name or plant extracts | Icariol | |
| PMID | 30763719 | |
| Literature evidence | Compounds 2, 6 and 18 showed significant antiproliferative effects against five human cancer cell lines (A549, MDA-MB-231, SK-Hep-1, SNU638, HCT116) with IC50 values ranging from 1.99 ± 0.41 μM to 15.18 ± 1.17 μM. | |
| IUPAC name | 4-[(2S,3R,4R,5S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-3,4-bis(hydroxymethyl)oxolan-2-yl]-2,6-dimethoxyphenol | |
| Phytochemicals’ class or type of plant extracts | NA | |
| Source of phytochemicals or plant Extracts | Zea mays | |
| Geographical availability | Guatemala, Mexico Central, Mexico Southwest | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Lung cancer, Colon cancer, Liver cancer, Stomach cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 4.86 ± 0.21 μM against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | HCT-116, MDA-MB-23, SK-HEP-1 and SNU-640 | |
| Additional information | Shows significant antiproliferative effects against five human cancer cell lines (A549, MDA-MB-231, SK-Hep-1, SNU638, HCT116) | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:426810-1 | |
| Safety | NA |